产品货号:
Z23321
中文名称:
PCSK6抗体
英文名称:
Anti-PCSK6 Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-PCSK6 Antibody |
指标别名 | proprotein convertase subtilisin/kexin type 6;PACE4;SPC4;PCSK6 |
克隆性 | Polyclonal |
检验物种 | human,mouse,rat |
应用范围 | WB |
基因名称 | PCSK6 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | A synthetic peptide corresponding to a sequence at the C-terminus of human PACE4 (614-651aa RNPEKQGKLKEWSLILYGTAEHPYHTFSAHQSRSRMLE),different from the related rat sequence by two amino acids. |
实际分子量 | 80,45/80/100KD |
成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
纯化方式 | Immunogen affinity purified. |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | Proprotein convertase subtilisin/kexin type 6 is an enzyme that in humans is encoded by the PCSK6 gene.This gene encodes a member of the subtilisin-like proprotein convertase family,which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway.The encoded protein undergoes an initial autocatalytic processing event in the ER to generate a heterodimer which exits the ER and sorts to the trans-Golgi network where a second autocatalytic event takes place and the catalytic activity is acquired.The encoded protease is constitutively secreted into the extracellular matrix and expressed in many tissues,including neuroendocrine,liver,gut,and brain.This gene encodes one of the seven basic amino acid-specific members which cleave their substrates at single or paired basic residues.Some of its substrates include transforming growth factor beta related proteins,proalbumin,and von Willebrand factor.This gene is thought to play a role in tumor progression and left-right patterning.Alternatively spliced transcript variants encoding different isoforms have been identified. |
Uniprot ID | P29122 |
推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
基因名全称 | proprotein convertase subtilisin/kexin type 6 |
蛋白名全称 | Proprotein convertase subtilisin/kexin type 6 |
推荐稀释比 | Western blot(WB) 1:500~2000 |
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